Doctors Best L Tryptophan
Best L-Tryptophan products contain Ajinomoto TryptoPure™. Tryptophan is an essential amino acid readily converted by the body to the neurotransmitter serotonin. Able to cross the blood-brain barrier, L-tryptophan is altered by enzymes to first form the intermediate amino acid 5-HTP and then serotonin. It is also the metabolic precursor to melatonin and to the B vitamin niacin. Supplementing the diet with pure L-tryptophan like TryptoPure™, found in Doctor’s Best L-Tryptophan products, can improve sleep and enhance mood, and may also be beneficial in reducing carbohydrate cravings.*
What is Ajinomoto TryptoPure™?
TryptoPure™ is pure, pharmaceutical-grade L-tryptophan produced by the world's leading maker of amino acids—Ajinomoto. The global leader in the research,production, and sales of amino acids, Ajinomoto was one of the first to make pharmaceutical-grade amino acids; they literally invented the process.
Ajinomoto TryptoPure™ is considered the purest, most trusted L-tryptophan available. It is manufactured via fermentation strictly from vegetable sources, not animal, and it is between 99% and 100% pure. The level of impurities in tryptophan from other makers can be much higher.
In fact, from 1989 to 2006 the FDA was so concerned about the quality of tryptophan coming into the U.S. that it instituted an import ban with one exception: Ajinomoto's TryptoPure™. In 1989, the importation of L-tryptophan was banned in the United States after cases of an autoimmune illness called eosinophilia-myalgia syndrome were traced to an improperly prepared batch of tryptophan.The FDA limited L-tryptophan availability to prescription drugs, infant formulas, and enteral feeding products. Because the FDA recognized the unsurpassed quality of Ajinomoto’s TryptoPure™, it was excepted from the ban, but its use was limited to those few products. Today, it is available over-the-counter in Doctor’s Best L-Tryptophan products.
Doctors Best L Tryptophan

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Product ID: DRB3212
| L-Tryptophan - 500 mg (90 veggie caps) by Doctor's Best | |
| List Price: | $33.99 |
| Sale Price: | $20.75 |
| You Save: | $13.24 (39% off) |
| Quantity: | |
| Availability: | In stock. Ships today (Thursday, May 17) if you order in the next 7 hours and 44 minutes |
- Science-based nutrition
- Dietary supplement
- Can improve sleep and enhance mood
- Suitable for vegetarians
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Suggested Usage
Take 1 or 2 capsules daily, or as recommended by a health care practitioner. For optimum absorption, take separately from protein-containing foods and dietary supplements containing protein or amino acids.
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Supplement Facts |
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| Amount per serving | % Daily Value |
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| Ajinomoto L-Tryptophan | 500 mg | † |
| † Daily Value not established |
Caution
Uncontaminated L-tryptophan has a thirty-year history of safety and absence of adverse effects at levels commonly consumed by humans. When administered in abnormally high dosages of 7 grams (for a 150 pound human) per day, potential side effects include gastric irritation, vomiting, and head twitching. Use during pregnancy or lactation has not been studied as of yet and is, therefore, not recommended. L-tryptophan should not be used by individuals taking antidepressant drugs without close medical supervision.
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