Fatty Liver Disease

What is Fatty Liver?
Fatty liver is the accumulation of fat in the liver. Simple fatty liver is not a disease, since it does not damage the liver, but is a condition that can be identified by taking a sample of liver tissue (liver biopsy) and examining it under a microscope. Another term often used to describe this condition is fatty infiltration of the liver.

What causes Fatty Liver?
Fat accumulates in the liver usually in connection with heavy use of alcohol, weight gain or diabetes. Fatty liver can also occur with poor diet and certain illnesses, such as tuberculosis, intestinal bypass surgery for obesity, and certain drugs such as corticosteroids.

Fatty Liver Fibrosis Cirrhosis

How is Fatty Liver identified?
Fatty liver is usually suspected in a patient with the diseases or conditions described above. The patient may have an enlarged liver or minor elevation of liver enzyme tests. Several studies show that fatty liver is one of the most common causes of mild elevation of liver blood tests found in routine blood screening.

To find out for certain whether a patient has fatty liver requires that a sample of liver tissue be obtained (biopsy). Images of the liver obtained by an ultrasound test or by a computed tomography (CT) scan can suggest the presence of a fatty liver. In the ultrasound test, a fatty liver will produce a bright image in a ripple pattern. A CT scan will show a liver that is less dense than normal.

How does fat get into the Liver?
It is not certain how fatty liver occurs. A patient has fatty liver when the fat increases the weight of the liver by 5%. Possible explanations for fatty liver include the transfer of fat from other parts of the body, or an increase in the extraction of fat presented to the liver from the intestine. Other explanations are that the liver reduces the rate it breaks down and removes fat. Eating fatty food by itself does not produce a fatty liver.

Can Fatty Liver lead to other liver diseases?
Patients who drink too much alcohol for many years may develop alcoholic liver damage that includes fatty liver. Alcoholism could also result in inflammation of the liver (alcoholic hepatitis) and/or scarring (alcoholic cirrhosis). Evidence suggests that while fatty liver is usually present in patients with excessive intake of alcohol, fatty liver does not by itself lead up to the development of alcoholic hepatitis or alcoholic cirrhosis.

An inflammation of the liver associated with an increase of fat deposits may occur in middle-aged, overweight, and often diabetic patients who do not drink alcohol. This disease, which resembles alcoholic hepatitis, is called nonalcoholic steatohepatitis (NASH). This fatty tissue in the liver may break up and the patient may develop cirrhosis (scarring of the liver). Some studies have shown that 20% to 40% of people who are grossly overweight will develop NASH. However, just because a patient is grossly overweight does not mean they will develop NASH. Some researchers have connected the development of NASH with poor control of diabetes mellitus, rapid weight loss, or in women, the taking of hormones (estrogen).

How can Fatty Liver be treated?
The treatment of fatty liver is related to the cause. It is important to remember that simple fatty liver does not require treatment, since it does not result in damage to liver cells or clinical disease. However, on some occasions it can be a sign that other more harmful conditions are at work. Fatty liver may be associated with or may lead to inflammation of the liver. Obese patients with fatty liver will have reduction or loss of excess fat in liver cells, as well as in other cells in the body, if substantial weight loss can be achieved. Patients who drink alcohol to excess will also have a loss of fat in the liver when alcohol is discontinued. Good control of diabetes with diet, drugs, or insulin also decreases the fat content in the liver.

Two products that are highly effective and recommended for fatty liver disease are the world's #1 selling liver formula Liv-52 and Milk Thistle (Silymarin). The top-selling liver support formula, Liv-52, can be ordered on this page.

Top-selling product for fatty liver disease:

Liv-52 was introduced in 1955. Since then, it has been sold worldwide and is recognized by over 200,000 health professionals as one of the most effective liver formulas, with beneficial effects reported in over 276 research studies on a variety of cases.

Liv-52 is clinically proven to result in definite improvement in Fatty Liver disease and a change in the architecture of the liver. Hepatic function tests and needle biopsy specimens demonstrate a definite improvement in hepatocellular function and structure. Liv-52 treatment ensures an increase in the number of the total mass of functioning hepatocytes. The liver enzymes return to normal levels with an increase in total proteins, albumin and hemoglobin after treatment with Liv-52.

Liv-52 ensures optimum liver function through the protection of the hepatic parenchyma, and by way of its potent antioxidant properties, it acts as a powerful detoxification agent. Liv-52 neutralizes all kind of toxins and poisons from food, water, air and medications, all sources of detrimental effects on the liver. Alcohol users in partucular find Liv-52 helpful in maintaining a healthier liver. It also helps those taking pharmaceutical drugs to protect themselves against the damaging side effects on the liver. In fatty liver disease, beneficial effects have been demonstrated in several clinical trials.

Research on Liv-52

Validated by 276 clinical trials and research studies.
Endorsed by over 200,000 healthcare professionals.
Approximately 2 billion tablets and 13 million syrup bottles of Liv-52 are sold every year worldwide. See photos

For complete research on clininal trials, experimental papers, and studies on Liv-52's effect on various forms of liver conditions, visit the Liv-52 Research Page.

Liv-52 in the News:

Himalaya's Liv-52 approved as an herbal drug for liver in Switzerland by its FDA equivalent. It is believed to be the first multi-herb remedy granted regulatory approval as a drug, which is an outstanding feat for an herbal product. Read more
Liv-52 - One of 13 herbal formulas included in the ABC Clinical Guide to Herbs. Read more
Journal of American Botanical Council, HerbalGram, publishes research review on Liv-52's beneficial effect in Liver Cirrhosis. Read more
Award-winning author of New York Times bestsellers, Nutrition expert and celebrity, Ann Louise Gittleman, Ph.D., C.N.S., recommends Liv-52 for a variety of liver problems. Read more
International Journal of Phytotherapy & Phytopharmacology, Phytomedicine publishes the clinical study on how Liv-52 "was found to be effective" in protecting and restoring the liver. Read more
America's beauty and lifestyle expert, Kat James, whose advice features in Ophra's magazine 'O', Vogue, Glamour, and whose clients include celebrities like Sarah Jessica Parker and Kate Hudson, speaks on how Liv-52 helped her with her own life threatening liver disease. Read more
Himalaya celebrates 75 years developing pharmaceutical-grade herbal formulations. Read more

Liv-52 comes in kosher certified clear and easy-to-swallow vegi-capsules that do not have any odor or taste. The new formula uses our proprietary herbal extract formulation process that increases concentration of active constituents and results in higher bioavailability. Suitable for vegetarians.

Liv.52 - Liver support formula (90 vegi-capsules)

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SIZE
Available in a pack of 90 vegi-capsules. Does not contain added sugar, salt, artificial colors, flavors or preservatives. Suitable for vegetarians.

SUGGESTED USE
Two vegi-capsules twice daily. Allow several weeks for full benefits. The use of natural products provides progressive but long-lasting results.

SIDE EFFECTS
None

DRUG INTERACTIONS
None

CONTRAINDICATIONS
None

Main Ingredients

The main ingredients in LiverCare/Liv.52 are:

Capers (Latin name: Capparis spinosa)
Caper is a hepatic stimulant that have been used for improving the functional efficiency of the liver. Recent experimental studies also confirm its protective action on the histological architecture of the liver and the positive effects on liver glycogen and serum proteins.

Chicory (Latin name: Cichorium intybus)
Chicory is a powerful hepatic stimulant which increases bile secretion, promotes digestion and enhances the action of Capers. Experimental evidence has been obtained of its effect on liver glycogen and recent studies have shown the inhibition of free radical induced DNA damage.

Black Nightshade (Latin name: Solanum nigrum)
The Black Nightshade plant and its berries contain various alkaloids that have been isolated and shown to have a dilating effect on the pupil. The main use, however, is to support a healthy liver, skin, kidneys and bladder. The most recent studies indicate that the hepatoprotective effect of the crude extract of Black Nightshade may be due to the suppression of the oxidative degradation of DNA.

Arjuna (Latin name: Terminalia arjuna)
Arjuna is a heart tonic that has been used to support cardiovascular functions since ancient times when it was discovered to have cardio-protective benefits. Recent studies have investigated the mechanism of this activity and has shown a dose-dependent regulation of blood pressure and heart rate. There was also a slight increase in the HDL-to-total cholesterol ratio and an overall improvement in the cardiovascular profile.

Negro Coffee (Latin name: Cassia occidentalis)
Negro Coffee has been traditionally used to promote normal bowel movements. It is a cousin species of Senna, a known and stronger purgative. Despite its name (which comes from its occasional use as a coffee substitute), Negro Coffee is absolutely unrelated to coffee.

Yarrow (Latin name: Achillea millefolium)
Yarrow has been traditionally used for support of the digestive and urinary functions. Its constitutents have been extensively studied and found to be of value as an alterative, diuretic, and tonic for the venous system. Additionally, Yarrow has been known to have a healing and soothing effect on the mucous membranes. It has been shown effective in regulating gastric and bile secretions.

Tamarisk (Latin name: Tamarix gallica)
Tamarisk, sometimes referred to as Saltcedar, has been traditionally used as a tonic and diuretic. It contains an alkaloid, Tamarixin, that has been linked to its effectiveness in conditions associated with hepatic insufficiency. There are indications that Tamarisk is also helpful in increasing platelet counts.

SCIENTIFIC VALIDATION
Liv.52 has been scientifically validated by many clinical studies. Its formula has been subjected to the modern scrutiny of clinical testing to prove its benefits in gently addressing your health concerns, and its quality is controlled by the most sophisticated chromatographic "fingerprinting" techniques.

Liv-52 Milestones :

More than 300 clinical studies, many double-blind, placebo-controlled, have been performed on Liv-52 since its introduction in 1955. Since then, it has become one of the most widely sold medications in the world and endorsed by over 200,000 healthcare professionals.
In what is believed to be the first herbal remedy granted regulatory approval as a drug, Liv-52 has recently been registered a safe and effective drug by the "Intercantonal Office for the Control of Medicines," Switzerland's equivalent of the United States' FDA.

Know your Liver:

Liver is the biggest and the most complex organ in the body with more than 500 functions
The liver is an "incredible chemical factory," producing many important chemical compounds needed to survive, such as bile, albumin, blood clotting factors, cholesterol, Vitamin E.
Converts amino acids (proteins) and lipids into glucose, a complex process catalyzed by a series of enzymes
Plays a major role in maintaining normal blood sugar levels, an important source of energy for the brain, heart and muscles.
Performs numerous other functions such as regulating lipids or metabolizing prescribed and over the counter drugs, alcohol, and many other ingested chemicals such as caffeine, etc.
Helps digest the food we eat and assists in ridding our body of many toxins.
Eliminates various harmful chemicals from the body. Treats about 1,300 ml of blood per minute, thereby acting as the body's "garbage disposal."

Liver dysfunctions may take many forms

4,000,000 people have Hepatitis C in the United States, causing 10,000 deaths every year.
Cirrhosis of the liver is the eighth leading cause of death in the United States - kills 25,000 people per year.
Commonly prescribed cholesterol-lowering medications such as statins (e.g. Lipitor), among many other chemical drugs, are known to be toxic to the liver.
Widely taken OTC medications are not as safe as they seem. For example, Acetaminophen (e.g. Tylenol) can be toxic to the liver and its toxicity can be accentuated by alcohol.
The American Journal of Emergency Medicine, notes that in one year, hospitals treated over 26,765 patients for alcohol toxicity and another 16,635 for Acetaminophen (Tylenol) toxicity.
Fatigue, aches, and pain in joints and muscles, frequent headaches, stress and appetite fluctuations may be signs of an over-worked liver.

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