Hepatitis C

World's #1 selling liver support formula

Liv-52 was introduced in 1955. Since then, it has been sold worldwide and is recognized by over 200,000 health professionals as one of the most effective liver formulas, with beneficial effects reported in over 276 research studies on a variety of cases. It has now become the top-selling and most researched proven herbal formula for liver diseases.

Liv-52 in clinically proven to result in improvement and a change in the architecture of the liver. Hepatic function tests and needle biopsy specimens demonstrate a definite improvement in hepatocellular function and structure. Liv-52 treatment ensures an increase in the number of the total mass of functioning hepatocytes. The liver enzymes return to normal levels with an increase in total proteins, albumin and hemoglobin after treatment with Liv-52.

Liv-52 ensures optimum liver function through the protection of the hepatic parenchyma, and by way of its potent antioxidant properties, it acts as a powerful detoxification agent. Liv-52 neutralizes all kind of toxins and poisons from food, water, air and medications, all sources of detrimental effects on the liver. Alcohol users in partucular find Liv-52 helpful in maintaining a healthier liver. It also helps those taking pharmaceutical drugs to protect themselves against the damaging side effects on the liver.

Liv-52 in the News:

• Himalaya's Liv-52 approved as an herbal drug for liver in Switzerland by its FDA equivalent. It is believed to be the first multi-herb remedy granted regulatory approval as a drug, which is an outstanding feat for an herbal product. Read more
• Liv-52 - One of 13 herbal formulas included in the ABC Clinical Guide to Herbs. Read more
• Journal of American Botanical Council, HerbalGram, publishes research review on Liv-52's beneficial effect in Liver Cirrhosis. Read more
• Award-winning author of New York Times bestsellers, Nutrition expert and celebrity, Ann Louise Gittleman, Ph.D., C.N.S., recommends Liv-52 for a variety of liver problems. Read more
• International Journal of Phytotherapy & Phytopharmacology, Phytomedicine publishes the clinical study on how Liv-52 "was found to be effective" in protecting and restoring the liver. Read more
• America's beauty and lifestyle expert, Kat James, whose advice features in Ophra's magazine 'O', Vogue, Glamour, and whose clients include celebrities like Sarah Jessica Parker and Kate Hudson, speaks on how Liv-52 helped her with her own life threatening Hepatitis. Read more
• Himalaya celebrates 75 years developing pharmaceutical-grade herbal formulations. Read more

Liv-52 comes in kosher certified clear and easy-to-swallow vegi-capsules that do not have any odor or taste. The new formula uses our proprietary herbal extract formulation process that increases concentration of active constituents and results in higher bioavailability. Suitable for vegetarians.

Liv.52 - Liver support formula (90 vegi-capsules)

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SIZE
Available in a pack of 90 vegi-capsules. Does not contain added sugar, salt, artificial colors, flavors or preservatives. Suitable for vegetarians.

SUGGESTED USE
Take one capsule twice daily before meals with a full glass of water. Increase the dosage to 4 capsules a day, if desired. Allow several weeks for full benefits. The use of natural products provides progressive but long-lasting results.

Main Ingredients

The main ingredients in LiverCare/Liv.52 are:

Capers (Latin name: Capparis spinosa)
Caper is a hepatic stimulant that have been used for improving the functional efficiency of the liver. Recent experimental studies also confirm its protective action on the histological architecture of the liver and the positive effects on liver glycogen and serum proteins.

Chicory (Latin name: Cichorium intybus)
Chicory is a powerful hepatic stimulant which increases bile secretion, promotes digestion and enhances the action of Capers. Experimental evidence has been obtained of its effect on liver glycogen and recent studies have shown the inhibition of free radical induced DNA damage.

Black Nightshade (Latin name: Solanum nigrum)
The Black Nightshade plant and its berries contain various alkaloids that have been isolated and shown to have a dilating effect on the pupil. The main use, however, is to support a healthy liver, skin, kidneys and bladder. The most recent studies indicate that the hepatoprotective effect of the crude extract of Black Nightshade may be due to the suppression of the oxidative degradation of DNA.

Arjuna (Latin name: Terminalia arjuna)
Arjuna is a heart tonic that has been used to support cardiovascular functions since ancient times when it was discovered to have cardio-protective benefits. Recent studies have investigated the mechanism of this activity and has shown a dose-dependent regulation of blood pressure and heart rate. There was also a slight increase in the HDL-to-total cholesterol ratio and an overall improvement in the cardiovascular profile.

Negro Coffee (Latin name: Cassia occidentalis)
Negro Coffee has been traditionally used to promote normal bowel movements. It is a cousin species of Senna, a known and stronger purgative. Despite its name (which comes from its occasional use as a coffee substitute), Negro Coffee is absolutely unrelated to coffee.

Yarrow (Latin name: Achillea millefolium)
Yarrow has been traditionally used for support of the digestive and urinary functions. Its constitutents have been extensively studied and found to be of value as an alterative, diuretic, and tonic for the venous system. Additionally, Yarrow has been known to have a healing and soothing effect on the mucous membranes. It has been shown effective in regulating gastric and bile secretions.

Tamarisk (Latin name: Tamarix gallica)
Tamarisk, sometimes referred to as Saltcedar, has been traditionally used as a tonic and diuretic. It contains an alkaloid, Tamarixin, that has been linked to its effectiveness in conditions associated with hepatic insufficiency. There are indications that Tamarisk is also helpful in increasing platelet counts.

SCIENTIFIC VALIDATION
Liv.52 has been scientifically validated by many clinical studies. Its formula has been subjected to the modern scrutiny of clinical testing to prove its benefits in gently addressing your health concerns, and its quality is controlled by the most sophisticated chromatographic "fingerprinting" techniques.

Research studies and clinical trials on Liv-52

For all research studies and clinical trials on Liv-52, please visit the Liv-52 Research Page

The efficacy of Liv-52 on liver cirrhotic patients: A randomized, double-blind, placebo-controlled first approach (PDF) - The results demonstrated that the patients treated with Liv-52 for 6 months had significantly better child-pugh score, decreased ascites, decreased serum ALT and AST.

A novel mechanism of action prevents ethanol-induced injury - Liv-52 profile of an herbal remedy (PDF) -

Liv-52 in the management of various hepatic disorders - A study of 53 cases (PDF) -

Role of Liv-52 in Indian childhood cirrhosis, with special reference to its effect on alpha-I-antitrypsin levels (PDF) -

Role of Liv-52 in management of Indian childhood cirrhosis (PDF) -

Role of Liv-52 in hepatic and cirrhosis of the liver (PDF) -

Liv-52 in the treatment of cirrhosis of liver - Certain observations (PDF) -

A study of therapeutic actions of Liv-52 on various stages, severity, and activity of portal cirrhosis and infective hepatitis (PDF) -

Study of Liv-52 therapy in cases of Indian childhood cirrhosis and other liver disorders (PDF) -

Management of steatorrhoea of cirrhosis of the liver by an indigenous drug Liv-52 (PDF) -

Liv-52 - A clinico-biochemical trial in hepatic cirrhosis (PDF) -

Hepatic cirrhosis in the tropics (PDF) -

Liv-52 - A new therapeutic agent in the management of steatorrhoea of cirrhosis of the liver (PDF) -

Long-term studies on the therapy of hepatic damage and cirrhosis of liver (PDF) -

Cirrhosis of liver - Results of treatment with an indigenous drug: Liv-52 (PDF) -

B.S.P. test in the evaluation of therapy in hepatic cirrhosis by an indigenous drug Liv-52 (PDF) -

Cirrhosis of liver (PDF) -

Liv-52 - Infantile cirrhosis (PDF) -

Clinical and histopathological evaluation of Liv-52 in cirrhosis in liver (PDF) -

Treatment of hepatopathy in children with a combination of capparis spinosa and other Indian indigenous drugs (PDF) -

Therapy of cirrhosis of liver and liver damage with indigenous drugs : Experimental and clinical studies (PDF) -

Liv-52 therapy in cirrhosis of liver in children (PDF) -

Treatment of infantile cirrhosis with an indigenous preparation (PDF) -

Some clinical observations on the use of Liv-52 (An indigenous drug) in cases of cirrhosis of liver in children (PDF) -

For all research studies and clinical trials on Liv-52, please visit the Liv-52 Research Page

Hepatitis C at a glance:

• In the U.S., hepatitis C virus (HCV) infection is the most common cause of chronic hepatitis, and the complications of hepatitis C virus cirrhosis are the most common reasons for liver transplantation.
• Hepatitis C virus is one of several viruses (A, B, C, D, and E) that can cause hepatitis (inflammation of the liver). hepatitis C virus is distinct from these other viruses.
• One of the major problems with hepatitis C virus is that 85% of individuals who are initially (acutely) infected with hepatitis C virus will become chronically (long duration) infected. About one third of individuals chronically infected with hepatitis C virus will progress to cirrhosis.
• Hepatitis C virus is spread (transmitted) through the blood. Intravenous drug abuse is the most common mode of transmission, while the risk of acquiring hepatitis C virus through sexual contact is quite low.
• Generally, patients do not develop symptoms until they have progressed to advanced cirrhosis. Some individuals, however, may have fatigue and other non-specific symptoms in the absence of cirrhosis. A minority of hepatitis C virus patients may have symptoms coming from involved organs outside of the liver.
• Hepatitis C is diagnosed by anti-hepatitis C virus antibody tests, which diagnosis is then confirmed by nucleic acid based tests for the virus itself. The amount of the virus in the blood (viral load) does not correlate with the severity of the disease.
• A liver biopsy is used to assess the amount of liver damage (liver cell injury and scarring), which may be important in determining the outcome (prognosis) and in planning treatment.
• Considerable progress has been made in the treatment of hepatitis C virus. For patients infected with genotype 2 or 3, successful treatment with combined interferon (conventional or pegylated) and ribavirin can be achieved in up to 80% of patients.
• Treatment for patients infected with genotype 1 hepatitis C virus, for whom the success rate with combined pegylated interferon and ribavirin is just under 50%, remains a challenge.
• Treatment is recommended for patients with detectable hepatitis C virus RNA who have persistently elevated liver tests and evidence of scarring and at least moderate inflammation on their liver biopsy, but without outward signs of liver failure.
• Treatment results in improvement in the inflammation and scarring of the liver in most sustained responders and also occasionally (and to a much lesser extent) in relapsers and non-responders.
• Clinical trials are underway to evaluate combinations of various antiviral agents and pegylated interferon in the treatment of hepatitis C.

LiverCare / Liv-52 Milestones :

• More than 300 clinical studies, many double-blind, placebo-controlled, have been performed on LiverCare /Liv-52 since its introduction in 1955. Since then, it has become one of the most widely sold medications in the world and endorsed by over 200,000 healthcare professionals.
• In what is believed to be the first herbal remedy granted regulatory approval as a drug, LiverCare / Liv-52 has recently been registered a safe and effective drug by the "Intercantonal Office for the Control of Medicines," Switzerland's equivalent of the United States' FDA.

Know your Liver:

• Liver is the biggest and the most complex organ in the body with more than 500 functions
• The liver is an "incredible chemical factory," producing many important chemical compounds needed to survive, such as bile, albumin, blood clotting factors, cholesterol, Vitamin E.
• Converts amino acids (proteins) and lipids into glucose, a complex process catalyzed by a series of enzymes
• Plays a major role in maintaining normal blood sugar levels, an important source of energy for the brain, heart and muscles.
• Performs numerous other functions such as regulating lipids or metabolizing prescribed and over the counter drugs, alcohol, and many other ingested chemicals such as caffeine, etc.
• Helps digest the food we eat and assists in ridding our body of many toxins.
• Eliminates various harmful chemicals from the body. Treats about 1,300 ml of blood per minute, thereby acting as the body's "garbage disposal."

Liver dysfunctions may take many forms

• 4,000,000 people have Hepatitis C in the United States, causing 10,000 deaths every year.
• Cirrhosis of the liver is the eighth leading cause of death in the United States - kills 25,000 people per year.
• Commonly prescribed cholesterol-lowering medications such as statins (e.g. Lipitor), among many other chemical drugs, are known to be toxic to the liver.
• Widely taken OTC medications are not as safe as they seem. For example, Acetaminophen (e.g. Tylenol) can be toxic to the liver and its toxicity can be accentuated by alcohol.
• The American Journal of Emergency Medicine, notes that in one year, hospitals treated over 26,765 patients for alcohol toxicity and another 16,635 for Acetaminophen (Tylenol) toxicity.
• Fatigue, aches, and pain in joints and muscles, frequent headaches, stress and appetite fluctuations may be signs of an over-worked liver.